Jia-Jie Chen Selected Research

tozasertib

1/2020	Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivo.
11/2013	Inhibition of mTOR pathway sensitizes acute myeloid leukemia cells to aurora inhibitors by suppression of glycolytic metabolism.
5/2011	Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells.

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Jia-Jie Chen Research Topics

Disease

8	Neoplasms (Cancer) 01/2020 - 11/2013
7	Hypersensitivity (Allergy) 05/2022 - 01/2019
6	Anaphylaxis (Anaphylactic Shock) 03/2022 - 01/2019
5	Inflammation (Inflammations) 03/2022 - 01/2019
4	Leukemia 03/2022 - 11/2016
3	Hepatocellular Carcinoma (Hepatoma) 03/2017 - 01/2016
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 11/2016 - 03/2014
3	Polyploidy 11/2016 - 11/2013
2	Liver Neoplasms (Liver Cancer) 09/2019 - 03/2017
2	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 01/2016
2	Acute Promyelocytic Leukemia 02/2012 - 05/2011
1	Crohn Disease (Crohn's Disease) 03/2021
1	Cytokine Release Syndrome 01/2021
1	Atopic Dermatitis (Atopic Eczema) 01/2021
1	COVID-19 01/2021
1	type 2C Congenital disorder of glycosylation 01/2020
1	Mastocytosis 01/2020
1	Stomach Neoplasms (Stomach Cancer) 01/2019
1	Lymphatic Metastasis 01/2019
1	Infections 03/2018
1	Osteosarcoma (Osteogenic Sarcoma) 01/2017
1	Epilepsy (Aura) 11/2016
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2013

Drug/Important Bio-Agent (IBA)

6	OvalbuminIBA 03/2022 - 01/2019
6	Immunoglobulin E (IgE)IBA 03/2022 - 01/2019
5	Pimozide (Orap)FDA Link 07/2020 - 01/2016
4	Human Serum Albumin FDA LinkGeneric 03/2022 - 01/2019
4	Pharmaceutical PreparationsIBA 01/2020 - 01/2016
4	Antipsychotic Agents (Antipsychotics)IBA 09/2019 - 01/2016
3	AntibodiesIBA 03/2022 - 01/2019
3	Immunoglobulins (Immunoglobulin)IBA 03/2022 - 01/2019
3	tozasertibIBA 01/2020 - 05/2011
2	Coloring Agents (Dyes)IBA 03/2022 - 02/2022
2	Histamine (Histamine Dihydrochloride)FDA Link 03/2022 - 01/2020
2	AntigensIBA 03/2022 - 01/2019
2	CytokinesIBA 01/2019 - 01/2017
2	AKI603IBA 11/2016 - 01/2015
2	Aurora Kinase AIBA 11/2016 - 01/2015
2	Imatinib Mesylate (Gleevec)FDA Link 11/2016 - 01/2015
2	Aurora KinasesIBA 11/2013 - 05/2011
2	AcidsIBA 02/2012 - 05/2011
2	RetinoidsIBA 02/2012 - 05/2011
1	Flavoring AgentsIBA 03/2022
1	HymecromoneIBA 02/2022
1	C-Reactive ProteinIBA 03/2021
1	Biomarkers (Surrogate Marker)IBA 03/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	tocilizumab (atlizumab)FDA Link 01/2021
1	3- (5- (4- (cyclopentyloxy)- 2- hydroxybenzoyl)- 2- ((3- hydroxy- 1,2- benzisoxazol- 6- yl)methoxy)phenyl)propionic acidIBA 01/2021
1	InterleukinsIBA 01/2021
1	OxazoloneIBA 01/2021
1	Monoclonal AntibodiesIBA 01/2021
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2021
1	phorbol-12-myristateIBA 01/2020
1	Calcium IonophoresIBA 01/2020
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2020
1	Hexosaminidases (Hexosaminidase)IBA 01/2020
1	Anti-Allergic Agents (Antiallergic Agents)IBA 01/2020
1	IgE Receptors (Fc epsilon RI)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	AlbuminsIBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 01/2019
1	EpitopesIBA 01/2019
1	ClusterinIBA 01/2019
1	AllergensIBA 01/2019
1	Verteporfin (Visudyne)FDA Link 01/2019
1	palbociclibIBA 01/2019
1	InterferonsIBA 01/2017
1	AmidesIBA 01/2017
1	CatalaseIBA 01/2017
1	Fluorouracil (Carac)FDA LinkGeneric 01/2017
1	Interleukin-2 (IL2)IBA 01/2017
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2017
1	Interleukin-2 Receptor alpha SubunitIBA 01/2017
1	mangostinIBA 03/2014
1	MTOR InhibitorsIBA 11/2013
1	Glucose (Dextrose)FDA LinkGeneric 11/2013
1	Sirolimus (Rapamycin)FDA Link 11/2013
1	4- (4- (N- benzoylamino)anilino)- 6- methoxy- 7- (3- (1- morpholino)propoxy)quinazolineIBA 11/2013
1	PP242IBA 11/2013
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2013
1	Deoxyglucose (2 Deoxy D glucose)IBA 11/2013
1	Decitabine FDA Link 02/2012

Therapy/Procedure

2	Therapeutics 05/2022 - 09/2019
1	Immunotherapy 11/2019
1	Intrauterine Devices (Intrauterine Device) 03/2018
1	Contraception (Birth Control) 03/2018
1	Drug Therapy (Chemotherapy) 03/2017